Structural determinants of trypsin affinity and specificity for cationic inhibitors
نویسندگان
چکیده
منابع مشابه
Structural and mechanistic determinants of affinity and specificity of ligands discovered or engineered by phage display.
The scope and utility of phage display is reviewed with emphasis on medical applications and structure-based ligand and drug design, from literature mostly after 1994. General principles by which phage-displayed peptides achieve affinity and selectivity for targets are described, along with selected structural or mechanistic studies of the binding of peptides or proteins discovered or engineere...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2008
ISSN: 0961-8368
DOI: 10.1110/ps.8.12.2621